A Treatise on Painting, by Leonardo da Vinci
1721
Senex and Taylor, London
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Take Notes of the Muscles and Tendons, which in different Attitudes, and different Motions are either discovered or hidden in each Member, or at least, that are neither the one nor the other: And remember that this is a study of great importance to Painters and Statuaries, whose Profession obliges them to Understand the Muscles, their Functions and Uses. But further, you must make these Remarks on the Human Body, in all its Stages, from Infancy to Old Age; observing the Changes each Member is liable to; for Instance, in growing fatter or leaner, &c.